Biological ageing has taken a leap with Omega-3.

Biological ageing has been hitting the headlines recently and the trigger for this is the publication of the DO-HEALTH trial showing omega-3 supplementation reduced biological age by 2.9 months.  

The study recruited 777 volunteers and gave 1g of omega-3 daily for 3 years. Biological age was measured using an array of epigenetic tests.  

Epigenetics are external modifications to DNA that switch genes on or off and several tests have been developed based on the tight association between chronological age and epigenetic status. What has caught the imagination of many is that the epigenetic clock can be modified, or slowed down, by life-style changes.  

The Swiss study showed that of the 3 interventions (omega-3, Vitamin D and exercise) Omega-3 supplementation was alone in reducing epigenetic age. However, greatest effects were seen when all 3 were given together.  

This is big news for the Omega-3 world because it’s rare that a single lifestyle change can have such a large impact on ageing and it has hit mainstream news.  

An example of the international interest:

Another reason for excitement around this research is the potential for causality. Many biomarkers of ageing do not have causality. The easiest example of this is grey hair. Few would contest that grey hair is marker of age, but dyeing hair black fails to reduce ageing because it is not a causative event. Epigenetics however, has widespread effects on gene expression and potentially could regulate age-related genes.  

Getting the lowest rate of ageing has become competitive with the self-styled Olympics ranging contestants by their rate of ageing, at  

The current world leader is Bryan Johnson, a guru in the field of longevity who invests 100 millions of USD in his quest against the inevitable, has the ambition of reversing his biological clock through an extreme regimen called the “Blueprint protocol”, and yes it includes healthy doses of EPA and DHA. You can follow Johnson or join the competition at Rejuvenation Olympics.  

Staying young is getting interesting.

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